OUR DEVICES

STYL’One Evo

STYL’One Evo, the most versatile single-punch tableting press for R&D, scale-up and production support. The all-purpose multilayer instrument for formulation development and early API characterization to scale-up at production speed which only needs a few grams of powder.

Features:
  • Force, displacement and radial measurements
  • Force mode for cost-saving on API characterization
  • Manual, advanced gravity and force feeding options
  • Innovative feed shoes for mini-tablets or tab-in-tab
  • Replication of all types of rotary tablet presses
  • Roll compaction mimicking for ultimate material sparing
R&D multilayer compaction simulator used for its versatility and scale up speed

STYL’One NANO

STYL’One Nano the revolutionary benchtop R&D tablet press for API characterization and formulation development which only needs a few grams of powder.

Features:
  • Force and displacement measurements
  • Force mode for cost-saving on API characterization
  • Manual, advanced gravity and innovative force feeding options for minitablets
  • R&D compression profiles (V-shape, extended dwell time, pre- and main compression)
R&D press for powder characterisation or small batch production

Radial Pressure

Standard compaction studies are made by analysis of the vertical forces on upper and lower punches. It is however well known that applying a vertical strain on the powder will induce vertical and horizontal stresses.

Extensive material characterization can be performed on STYL’One™ Evo by installing an instrumented die to measure the die-wall pressure. Maximum Die wall Pressure (MDP) and Residual Die wall Pressure (RDP), before ejection, are commonly used parameters in the industry. The instrumented die is a powerful tool to understand and predic tablet defects.

Measure 'die wall' force to analyse capping tendencies

Pycnometer

Gas pycnometry is recognized as one of the most reliable techniques for obtaining true density. This technique is non-destructive as it uses Helium displacement method to measure volume.

Our Science Lab can measure the true density with the Micromeritics Accupyc II 1360, enabling porosity analysis and solid fraction determination during material characterization or roller compaction study.

Measure relative density used in roll compacting studies

Semi-Automatic Tablet Tester

A SOTAX SmartTest 50 measures tablet weight, thickness, diameter, width and tablet breaking force (hardness). Data are automatically transferred to the Analysis Software of STYL’One instruments

Speed up studies and prevent mistakes with automatic data transfer to tablet press

Ancillary Equipment

  • Turbula mixer
  • Friability tester
  • Disintegration apparatus
Uniform mixing of small batches of products
Mass reduction of compressed, uncoated tablets occurring when subjected to mechanical stress during handling & packaging.
Mass reduction of compressed, uncoated tablets occurring when subjected to mechanical stress during handling & packaging.
Disintegration testing determines whether tablets or capsules disintegrate within a defined period of time when placed in a liquid medium

External Lubrication

Our tablet presses are equipped with a dispensing system to allow automatic external lubrication of punches and dies and avoid die sticking/ tightening without adding lubricant in the formulation. Thanks to this capability, our Science Lab can quickly assess the feasibility of external lubrication versus internal lubrication.

Test of external lubrication for pure API testing and tablets production
Advantageously replace alternative methods such a brush + vacuum or swab of magnesium stearate dispersed in a solvent

GMP Module

GMP Production Module comes with weight regulation system, the exact same way industrial rotary presses work. After entering a force setpoint, a regulation band and ejection band, STYL’One™ will automaticale the depth of fill in order to keep the compression force within the regulation band.

Production of tablet in a clean GMP manner.
Allows production of batches with GMP control, weight control and reporting
Tablet quality inspection to verify aspect

Environment Control

Our lab environment is controlled in temperature and humidity, we are able to lower hygrometry for specific needs like effervescent tablets.

Humidity of the lab is controlled and measured.

Milling and sifting with Quadro SLS

Our Science Lab is equipped with a multi-head Quadro SLS offering five milling and processing solutions. The SLS gives the reassurance that particle sizes and distributions achieved in the lab can be directly transferred to the production-scale equipment. Get in touch with us to explore milling process!

Quadro SLS, multi-head, hammer mill, conical mill, particle size distribution, PSD, size reducer

Small volume Caleva Mini Coater

The Caleva mini coater is designed for very small batches down to single tablet coating, a plus for material sparing and testing.

The Caleva mini coater is designed for very small batches down to single tablet coating.A plus for material sparing and testing